I can't backup
 

I can select the drive to back-up and the drive to back-up to, but I get no button to make it all happen or any scripots to choose from.

Everything else in the window is grayed out. This has worked perfectly for months then all of a sudden...poof, it stops working.

Help?

Quit SD!, remove the "Saved Settings" folder in Library/Application Support/SuperDuper! (off your Home folder), then restart SD! and see if that fixes it.